Pharmacokinetic analysis of plasma curves obtained after i.v. injection of the PET radioligand [11C] raclopride provides a likely explanation for rapid radioligand metabolism

Author:

Sestini Stelvio,Halldin Christer,Mansi Luigi,Castagnoli Antonio,Farde Lars

Publisher

Wiley

Subject

Cell Biology,Clinical Biochemistry,Physiology

Reference30 articles.

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3. Pharmacokinetics of sertindole and its metabolite dehydrosertindole in rats and characterization of their comparative pharmacodynamics based on in vivo D2 receptor occupancy and behavioural conditioned avoidance response;Bundgaard;Bioppharm Drug Dispos,2009

4. Pharmacokinetics of radiotracers in human plasma during positron emission tomography;Cumming;Synapse,1999

5. Radioligand studies in brain: Kinetic analysis of PET data;Cunningham;Med Chem Res,1995

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