tPA variant tPA-A296-299Prevents impairment of cerebral autoregulation and necrosis of hippocampal neurons after stroke by inhibiting upregulation of ET-1-Reference-Cited by-同舟云学术

tPA variant tPA-A296-299Prevents impairment of cerebral autoregulation and necrosis of hippocampal neurons after stroke by inhibiting upregulation of ET-1

Published:2017-07-13 Issue:1 Volume:96 Page:128-137
ISSN:0360-4012
Container-title:Journal of Neuroscience Research
language:en
Short-container-title:J Neuro Res

Author:

Armstead William M.¹²^ORCID,Hekierski Hugh¹,Yarovoi Serge³,Higazi Abd Al-Roof³⁴,Cines Douglas B.³

Affiliation:

1. Departments of Anesthesiology and Critical Care; University of Pennsylvania; Philadelphia PA l9l04

2. Department of Pharmacology; University of Pennsylvania; Philadelphia PA l9l04

3. Department of Pathology and Laboratory Medicine; University of Pennsylvania; Philadelphia PA l9l04

4. Department of Clinical Biochemistry; Hebrew University-Hadassah Medical School; Jerusalem Israel

Funder

National Institute of Neurological Disorders and Stroke

NIH

Publisher

Wiley

Subject

Cellular and Molecular Neuroscience

Reference42 articles.

1. Glutamate-induced neuronal death: a succession of necrosis or apoptosis depending on michondrial function;Ankarcrona;Neuron,1995

2. Role of endothelin-1 in age dependent cerebrovascular hypotensive responses after brain injury;Armstead;Am J Physiol,1999

3. NOC/oFQ and NMDA contribute to piglet hypoxic ischemic hypotensive cerebrovasodilation impairment;Armstead;Ped Res,2002

4. Age-dependent NMDA contribution to impaired hypotensive cerebral hemodynamics following brain injury;Armstead;Develop Brain Res,2002

5. Endothelins and the role of endothelin antagonists in the management of posttraumatic vasospasm;Armstead;Curr Pharm Des,2004

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1. Retraction Note: Release of IL-6 After Stroke Contributes to Impaired Cerebral Autoregulation and Hippocampal Neuronal Necrosis Through NMDA Receptor Activation and Upregulation of ET-1 and JNK;Translational Stroke Research;2024-06-06

2. Regulation of the Cerebral Circulation During Development;Comprehensive Physiology;2021-09-23

3. Relevance of Porcine Stroke Models to Bridge the Gap from Pre-Clinical Findings to Clinical Implementation;International Journal of Molecular Sciences;2020-09-08

4. Circulating tPA contributes to neurovascular coupling by a mechanism involving the endothelial NMDA receptors;Journal of Cerebral Blood Flow & Metabolism;2019-10-30

5. Structural Biology and Protein Engineering of Thrombolytics;Computational and Structural Biotechnology Journal;2019