Synthesis of Fused Lactones through Transition‐Metal‐Catalyzed peri C−H Functionalization

Abstract

AbstractThe rhodium(III)‐catalyzed dehydrogenative cyclization of 9‐anthracenecarboxylic acids and 2‐substituted 1‐naphthoic acids proceeds through peri C−H bond cleavages to produce fused lactones. These aromatic carboxylic acids also undergo dehydrogenative coupling with styrenes and successive Wacker‐type cyclization under palladium catalysis to construct 3‐benzylidenebenzo[de]isochromen‐1‐one frameworks.