Affiliation:
1. School of Chemistry and Environmental Engineering Wuhan Institute of Technology Wuhan 430205 China
2. School of Chemistry and Chemical Engineering Henan Normal University Xinxiang 453007 China
3. State Key Laboratory of Environmental Chemistry and Ecotoxicology Research Center for Eco-Environmental Sciences Chinese Academy of Science Beijing 100085 China
Abstract
AbstractThe derivatives of indoles are very useful intermediates in pharmaceuticals and organic synthesis. The efficient synthesis of the indole blocks and related functionalizations, especially the alkylation of indoles are hot topics in recent years. This review will focus on the following two aspects: i) new developments for the synthesis of indoles which was catalyzed by transition metals, the alkylation of indoles, including the one on N1‐position, C2‐position, as well as C3‐position. 1. Introduction 2. Synthesis of indoles catalyzed by various metals 2.1. Synthesis of indoles by palladium catalysts 2.2. Synthesis of indoles by other metal catalysts 3. Alkylation of indoles 3.1. N1‐alkylation of indoles 3.2. C2‐alkylation of indoles 3.3. C3‐alkylation of indoles
Funder
Henan Normal University
State Key Laboratory of Environmental Chemistry and Ecotoxicology
Chinese Academy of Sciences
Natural Science Foundation of Henan Province
Cited by
6 articles.
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