Formal [4+1] Cyclization of ortho ‐ or para ‐Quinone Methides with 3‐Chlorooxindoles: Synthesis of 3,2′‐Tetrahydrofuryl Spirooxindoles-Reference-Cited by-同舟云学术

Formal [4+1] Cyclization of ortho ‐ or para ‐Quinone Methides with 3‐Chlorooxindoles: Synthesis of 3,2′‐Tetrahydrofuryl Spirooxindoles

Published:2021-08-10 Issue:9 Volume:10 Page:2385-2396
ISSN:2193-5807
Container-title:Asian Journal of Organic Chemistry
language:en
Short-container-title:Asian J. Org. Chem.

Author:

Tian Xiaochen¹,Zhang Xiaoli¹,Hou Xiaohan¹,Ren Weiwu¹²,Li Xiaoyang¹,Zhao Fei³,Tao Houchao³,Wang Yang¹²

Affiliation:

1. Molecular Synthesis Center & Key Laboratory of Marine Drugs Chinese Ministry of Education School of Medicine and Pharmacy Ocean University of China 5 Yushan Road Qingdao 266003 P. R. China

2. Laboratory for Marine Drugs and Bioproducts Qingdao National Laboratory for Marine Science and Technology (QNLM) Qingdao 266237 P. R. China

3. iHuman Institute ShanghaiTech University Ren Building 393 Middle Huaxia Rd, Pudong New District Shanghai 201210 P. R. China

Funder

Fundamental Research Funds for the Central Universities

Publisher

Wiley

Subject

Organic Chemistry

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/ajoc.202100363

Reference87 articles.

2. Therapeutic Potential of Spirooxindoles as Antiviral Agents

3. Molecular diversity of spirooxindoles. Synthesis and biological activity

4. Discovery of orally active anticancer candidate CFI-400945 derived from biologically promising spirooxindoles: Success and challenges

5. The use of spirocyclic scaffolds in drug discovery

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