Synthesis of Trifluoromethyl‐Containing 2,3‐Dihydrobenzofurans via a Formal [4+1] Annulation of In‐situ Generated o‐Quinone Methides and CF3−Imidoyl Sulfoxonium Ylides

Author:

Sun Yue1,Ling Sihao1,Chen Zhengkai1ORCID

Affiliation:

1. School of Chemistry and Chemical Engineering Key Laboratory of Surface & Interface Science of Polymer Materials of Zhejiang Province Zhejiang Sci-Tech University Hangzhou 310018 China

Abstract

AbstractA metal‐free [4+1] annulation of in‐situ generated ortho‐quinone methides (o‐QMs) and CF3−imidoyl sulfoxonium ylides (TFISYs) has been achieved under mild conditions, which provides a facile and straightforward access to a variety of trifluoromethyl‐containing 2,3‐dihydrobenzofurans in moderate to excellent yields.

Funder

Natural Science Foundation of Zhejiang Province

Department of Education of Zhejiang Province

Publisher

Wiley

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