Copper‐Promoted Oxidative Amide‐Assisted Radical Selenylation of Anilides and N‐Arylsulfonamides with Diselenides

Abstract

AbstractA direct selenylation of N‐arylsulfonamides and anilides using environmentally friendly and readily available copper promoted assisted by amide is presented. This method provided convenient access for various selenylation reactions, demonstrating a wide range of substrates and strong tolerance to various functional groups. According to the selection of reaction substrates, products can be isolated to obtain a regioselectivity ortho‐, para‐, or unprecedented ortho, para‐diselenylation products. Such transformation was elucidated by a proposed copper‐promoted amide‐assisted radical mechanism.