Affiliation:
1. College of Chemical and Pharmaceutical Engineering Hebei University of Science and Technology NO. 26 Yuxiang Rd. Shijiazhuang 050018 P. R. China
2. Department of Pharmaceutical Engineering Hebei Chemical and Pharmaceutical College NO.88 Fangxing Rd. Shijiazhuang 050026 P. R. China
Abstract
AbstractWe report herein a practical protocol for the synthesis of symmetrical disulfides under atmospheric pressure, utilizing 1 mol% ABNO (9‐Azabicyclo[3.3.1]nonane N‐oxyl) as an efficient catalyst and O2 as terminal oxidant. Thiophenols and aliphatic thiols could be oxidized smoothly to give disulfides in 70%–90% yields. This method has advantages such as high atom‐economy, commercially available catalyst, broad substrate scope and mild reaction conditions, providing researchers a simple and attractive way to synthesize disulfides.
Funder
Natural Science Foundation of Hebei Province