Synthesis of Arylamines via a Tandem Petasis Borono‐Mannich/ Nucleophilic Substitution Reaction-Reference-Cited by-同舟云学术

Synthesis of Arylamines via a Tandem Petasis Borono‐Mannich/ Nucleophilic Substitution Reaction

Published:2023-05-11 Issue:6 Volume:12 Page:
ISSN:2193-5807
Container-title:Asian Journal of Organic Chemistry
language:en
Short-container-title:Asian J Org Chem

Author:

Li Guang‐Lin¹,Chen Yu²,Li Xiang‐Sai²,Yang Qi¹,Gu Ying‐Chun¹,Yu Ya‐Qin³,Xu Da‐Zhen²^ORCID

Affiliation:

1. Tianjin Engineering Technology Center of Chemical Wastewater Source Reduction and Recycling School of Science Tianjin Chengjian University Tianjin 300384 China

2. National Engineering Research Center of Pesticide (Tianjin) College of Chemistry Nankai University Tianjin 300071 China

3. Key Laboratory for Water Environment and Resources Tianjin Normal University Tianjin 300387 China

Abstract

AbstractAn efficient and practical one‐pot reaction for the synthesis of diarylmethyl anilines from easy available materials of salicylaldehydes, arylboronic acids and aromatic amines has been successfully developed. All the reactions proceed smoothly under transition‐metal‐free conditions via a p‐TSA promoted tandem Petasis borono‐Mannich/ nucleophilic substitution reaction, providing highly functionalized amines with wide functional groups in good to excellent yields. A reasonable explanation for this transformation was suggested.

Publisher

Wiley

Subject

Organic Chemistry

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/ajoc.202300174

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