Recent Advance in the β‐Stereoselective Synthesis of 2‐Deoxy Glycosides

Author:

Zhang Qiang1,Dong Hai2ORCID

Affiliation:

1. Hubei Key Laboratory of Purification and Application of Plant Anti-cancer Active Ingredients Hubei University of Education Second Gaoxin Road 129 Wuhan 430205 P.R. China

2. Key Laboratory of Materials Chemistry for Energy Conversion and Storage Ministry of Education School of Chemistry & Chemical Engineering Huazhong University of Science & Technology Luoyu Road 1037 430074 Hongshan Wuhan P.R. China

Abstract

AbstractCompounds containing a 2‐deoxy β‐glycoside linkage play important roles in carbohydrate chemistry, serving as potential therapies with significant biological properties. From the viewpoint of synthesis, many strategies developed in recent years targeted the stereoselective construction of 2‐deoxy glycosides. This review aims to summarise recent advances in the synthetic routes toward 2‐deoxy β‐glycosides developed over the last decade. Where associated, practical applications of these strategies in the total synthesis of natural products are highlighted.

Publisher

Wiley

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