Prophylactic window therapy with the clinical poly(ADP-ribose) polymerase inhibitor olaparib delays BRCA1-deficient mammary tumour formation in mice
Author:
Affiliation:
1. Division of Molecular Pathology and Cancer Genomics Netherlands; The Netherlands Cancer Institute; Amsterdam The Netherlands
2. MCCA Preclinical Intervention Unit; The Netherlands Cancer Institute; Amsterdam The Netherlands
Funder
Seventh Framework Programme
Publisher
Wiley
Subject
Pathology and Forensic Medicine
Reference49 articles.
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5. Population BRCA1 and BRCA2 mutation frequencies and cancer penetrances: a kin-cohort study in Ontario, Canada;Risch;J Natl Cancer Inst,2006
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1. Sustained, local delivery of the PARP inhibitor talazoparib prevents the development of mammary gland hyperplasia in Brca1-deficient mice;Scientific Reports;2021-01-13
2. Using Informatics Tools to Identify Opportunities for Precision Medicine in Diffuse Large B-cell Lymphoma;Clinical Lymphoma Myeloma and Leukemia;2020-04
3. BRCA1 -associated mammary tumorigenesis is dependent on estrogen rather than progesterone signaling;The Journal of Pathology;2018-07-04
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