Drug‐Induced Liver Injury due to Flucloxacillin: Relevance of Multiple Human Leukocyte Antigen Alleles

Author:

Nicoletti Paola12,Aithal Guruprasad P.3,Chamberlain Thomas C.45,Coulthard Sally4,Alshabeeb Mohammad46,Grove Jane I.37,Andrade Raul J.89,Bjornsson Einar10,Dillon John F.11,Hallberg Par12,Lucena M. Isabel89,Maitland‐van der Zee Anke H.13,Martin Jennifer H.14,Molokhia Mariam15,Pirmohamed Munir16,Wadelius Mia12,Shen Yufeng1718,Nelson Matthew R.19,Daly Ann K.4,

Affiliation:

1. Department of Genetics and Genomic SciencesIcahn School of Medicine at Mount Sinai New York New York USA

2. Sema4, a Mount Sinai Venture Stamford Connecticut USA

3. National Institute for Health Research (NIHR) Nottingham Biomedical Research CentreNottingham University Hospital NHS Trust and University of Nottingham Nottingham UK

4. Institute of Cellular MedicineNewcastle University Newcastle upon Tyne UK

5. University of British ColumbiaVancouver British Columbia Canada

6. Developmental Medicine DepartmentKing Abdullah International Medical Research Center Riyadh Kingdom of Saudi Arabia

7. Nottingham Digestive Diseases CentreSchool of MedicineUniversity of Nottingham Nottingham UK

8. UGC Digestivo y Servicio de Farmacología ClínicaInstituto de Investigación Biomédica de Málaga (IBIMA)Hospital Universitario Virgen de la VictoriaUniversidad de MálagaMálagaSpain

9. Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd)MadridSpain

10. Division of Gastroenterology and HepatologyDepartment of Internal MedicineThe National University Hospital of Iceland Reykjavik Iceland

11. Medical Research InstituteUniversity of DundeeNinewells Hospital Dundee UK

12. Department of Medical Sciences and Science for Life LaboratoryUppsala University Uppsala Sweden

13. Department of Respiratory MedicineAcademic Medical Center (AMC)University of Amsterdam Amsterdam The Netherlands

14. School of Medicine and Public HealthUniversity of Newcastle Callaghan New South Wales Australia

15. School of Population Health and Environmental SciencesFaculty of Life Sciences and MedicineKing's College London UK

16. Department of Molecular and Clinical PharmacologyUniversity of Liverpool Liverpool UK

17. The Herbert Irving Comprehensive Cancer CenterColumbia University New York New York USA

18. Department of Biomedical InformaticsColumbia University New York New York USA

19. Target SciencesGSK King of Prussia Pennsylvania USA

Funder

Abbott Laboratories

Amgen

Daiichi-Sankyo

GlaxoSmithKline

Merck

Novartis

Pfizer

Roche

Sanofi

Wellcome Trust

Biotechnology and Biological Sciences Research Council

National Institute for Health Research

Nottingham University Hospitals NHS Trust

University of Nottingham

European Regional Development Fund

Instituto de Salud Carlos III

Svenska Läkaresällskapet

Vetenskapsrådet

King’s College London

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

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