Pretreatments for enhancing clarification efficiency of depth filtration during production of monoclonal antibody therapeutics
Author:
Affiliation:
1. Research and Development Biocon Research Limited, Biocon Special Economic Zone Bangalore India
2. Department of Chemical Engineering Indian Institute of Technology New Delhi India
Publisher
Wiley
Subject
Biotechnology
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1002/btpr.2996
Reference37 articles.
1. Depth filtration: Cell clarification of bioreactor offloads
2. Primary clarification of very high‐density cell culture harvests by enhanced cell settling;Schirmer EB;Bioprocess Int,2010
3. Process cost and facility considerations in the selection of primary cell culture clarification technology
4. Clarification of recombinant proteins from high cell density mammalian cell culture systems using new improved depth filters
5. Exploitation of the Adsorptive Properties of Depth Filters for Host Cell Protein Removal during Monoclonal Antibody Purification
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2. Single‐use centrifugal separator enables intensification of the clarification process in biomanufacturing of recombinant proteins;Journal of Chemical Technology & Biotechnology;2023-03-10
3. Qualification of a Single‐Use Disk Stack Separator for Cell Separation in Mammalian Cell‐Based Antibody Production;Chemie Ingenieur Technik;2022-11-08
4. Fluidized bed centrifugation of precipitated and flocculated cell cultures: An intensified clarification approach for monoclonal antibodies;Journal of Biotechnology;2022-06
5. Depth filtration in bioprocessing — new opportunities for an old technology;Current Opinion in Chemical Engineering;2021-12
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