Endogenous Probes for Drug Transporters: Balancing Vision With Reality-Reference-Cited by-同舟云学术

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Endogenous Probes for Drug Transporters: Balancing Vision With Reality

Published:2017-07-14 Issue:3 Volume:103 Page:434-448
ISSN:0009-9236
Container-title:Clinical Pharmacology & Therapeutics
language:en
Short-container-title:Clin. Pharmacol. Ther.

Author:

Rodrigues AD¹,Taskar KS²,Kusuhara H³,Sugiyama Y⁴

Affiliation:

1. Pharmacokinetics; Dynamics & Metabolism, Medicine Design, Pfizer Inc.; Groton Connecticut USA

2. Mechanistic Safety and Disposition; IVIVT, GlaxoSmithKline; Ware Hertfordshire UK

3. Laboratory of Molecular Pharmacokinetics; Graduate School of Pharmaceutical Sciences, University of Tokyo; Tokyo Japan

4. RIKEN Innovation Center; Research Cluster for Innovation; RIKEN Kanagawa Japan

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Reference74 articles.

1. Applications of high-throughput ADME in drug discovery.;Kassel;Curr. Opin. Chem. Biol.,2004

2. In silico ADME/Tox: the state of the art.;Ekins;J. Mol. Graph. Model.,2002

3. Pharmacokinetic modeling of the hepatobiliary transport mediated by cooperation of uptake and efflux transporters.;Kusuhara;Drug Metab. Rev.,2010

4. Physiologically based pharmacokinetics is impacting drug development and regulatory decision making.;Rowland;CPT Pharmacometrics Syst. Pharmacol.,2015

5. The use of transporter probe drug cocktails for the assessment of transporter-based drug-drug interactions in a clinical setting-proposal of a four component transporter cocktail.;Ebner;J. Pharm. Sci.,2015

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