Loss in body weight is an independent prognostic factor for mortality in chronic heart failure: insights from the GISSI-HF and Val-HeFT trials

Author:

Rossignol Patrick123,Masson Serge4,Barlera Simona4,Girerd Nicolas123,Castelnovo Angelo4,Zannad Faiez123,Clemenza Francesco5,Tognoni Gianni6,Anand Inder S.7,Cohn Jay N.8,Anker Stefan D.910,Tavazzi Luigi11,Latini Roberto4,

Affiliation:

1. INSERM; Centre d'Investigations Cliniques-Plurithématique 1433; Nancy France

2. Université de Lorraine; France

3. INSERM U1116; Nancy France

4. Department of Cardiovascular Research; IRCCS-Istituto di Ricerche Farmacologiche Mario Negri; Milan Italy

5. Heart Failure Unit-ISMETT (Istituto Mediterraneo per i Trapianti e Terapie ad Alta Specializzazione); Palermo Italy

6. Fondazione Mario Negri Sud; Santa Maria Imbaro Italy

7. Veterans Affairs Medical Center and University of Minnesota; Minneapolis MN USA

8. Cardiovascular Division; University of Minnesota Medical School; Minneapolis MN USA

9. Department of Innovative Clinical Trials; University Medical Centre Göttingen; Göttingen Germany

10. Institute of Diabetes for Older People (IDOP); University of Bedfordshire; UK

11. GVM Hospitals of Care and Research; E.S Health Science Foundation; Cotignola Italy

Funder

Reagents for measuring NT-proBNP in Val-HeFT and GISSI-HF were kindly provided by Roche Diagnostics GmbH.

the European Commission’s Seventh Framework Programme

The GISSI-HF trial was supported by grants from Società Prodotti Antibiotici (SPA, Italy), Pfizer, Sigma Tau and AstraZeneca.

The Val-HeFT trial was funded by Novartis Pharmaceuticals (Switzerland).

Publisher

Wiley

Subject

Cardiology and Cardiovascular Medicine

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