Efficacy of Tocilizumab in Conventional Treatment-Refractory Adult-Onset Still's Disease: Multicenter Retrospective Open-Label Study of Thirty-Four Patients

Author:

Ortiz-Sanjuán Francisco1,Blanco Ricardo1,Calvo-Rio Vanesa1,Narvaez Javier2,Rubio Romero Esteban3,Olivé Alejandro4,Castañeda Santos5,Gallego Flores Adela6,Hernández M. Victoria7,Mata Cristina1,Ros Vilamajo Inmaculada8,Sifuentes Giraldo Walter Alberto9,Caracuel Miguel A.10,Freire Mercedes11,Gómez Arango Catalina12,Llobet José13,Manrique Arija Sara14,Marras Carlos15,Moll-Tuduri Concepción16,Plasencia-Rodriguez Chamaida17,Roselló Rosa18,Urruticoechea Ana19,Velloso-Feijoo Maria L.20,del Blanco Jordi21,González-Vela M. Carmen1,Rueda-Gotor Javier1,Pina Trinitario1,Loricera Javier1,González-Gay Miguel A.1

Affiliation:

1. Hospital Universitario Marqués de Valdecilla and Instituto de Investigación Marqués de Valdecilla (IDIVAL); Santander Spain

2. Hospital Universitario de Bellvitge, Hospitalet; Barcelona Spain

3. Hospital Universitario Virgen del Rocío; Seville Spain

4. Hospital Universitario Germans Trias i Pujol; Badalona Spain

5. Hospital Universitario de La Princesa, IIS Princesa Madrid; Madrid Spain

6. Hospital de Mérida; Mérida Spain

7. Hospital Clinic of Barcelona; Barcelona Spain

8. Hospital Son Llàtzer; Palma de Mallorca Spain

9. Hospital Ramón y Cajal; Madrid Spain

10. Hospital Reina Sofía; Córdoba Spain

11. Hospital Universitario Juan Canalejo; La Coruña Spain

12. Hospital Universitario Basurto; Bilbao Spain

13. Hospital Sant Pau; Barcelona Spain

14. Urgencias Hospital Regional Universitario Carlos Haya; Málaga Spain

15. Hospital Universitario Virgen de la Arrixaca; Murcia Spain

16. Hospital Mateu Orfila; Mahón Spain

17. Hospital Universitario La Paz; Madrid Spain

18. Hospital San Jorge; Huesca Spain

19. Hospital Can Misses; Ibiza Spain

20. Hospital Valme; Seville Spain

21. Hospital Sant Jaume; Calella Spain

Publisher

Wiley

Subject

Immunology,Rheumatology,Immunology and Allergy

Reference16 articles.

1. Adult onset Still's disease: review of 41 cases;Riera;Clin Exp Rheumatol,2011

2. Adult-onset Still disease as the cause of fever of unknown origin;Crispin;Medicine (Baltimore),2005

3. Elevated serum interleukin 6, interferon-γ, and tumor necrosis factor-α levels in patients with adult Still's disease;Hoshino;J Rheumatol,1998

4. Cytokine and immunogenetic profiles in Japanese patients with adult Still's disease: association with chronic articular disease;Fujii;Rheumatology (Oxford),2001

5. Association of intercellular adhesion molecule-1 with clinical manifestations and interleukin- 18 in patients with active, untreated adult-onset Still's disease;Chen;Arthritis Rheum,2005

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