Safety, Tolerability, and Pharmacokinetics of ARC-520 Injection, an RNA Interference-Based Therapeutic for the Treatment of Chronic Hepatitis B Virus Infection, in Healthy Volunteers-Reference-Cited by-同舟云学术

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Safety, Tolerability, and Pharmacokinetics of ARC-520 Injection, an RNA Interference-Based Therapeutic for the Treatment of Chronic Hepatitis B Virus Infection, in Healthy Volunteers

Published:2016-12-12 Issue:4 Volume:6 Page:350-362
ISSN:2160-763X
Container-title:Clinical Pharmacology in Drug Development
language:en
Short-container-title:Clinical Pharmacology in Drug Development

Author:

Schluep Thomas¹,Lickliter Jason²,Hamilton James¹,Lewis David L.¹,Lai Ching-Lung³,Lau Johnson YN⁴,Locarnini Stephen A.⁵,Gish Robert G.⁶,Given Bruce D.¹

Affiliation:

1. Arrowhead Pharmaceuticals, Inc.; Pasadena CA USA

2. Nucleus Network; Melbourne Australia

3. The University of Hong Kong; Hong Kong China

4. The Hong Kong Polytechnic University; Hong Kong China

5. Victorian Infectious Diseases Reference Laboratory; Victoria Australia

6. Division of Gastroenterology and Hepatology; Department of Medicine; Stanford University Medical Center; Stanford CA USA

Funder

Arrowhead Pharmaceuticals, Inc.

Publisher

Wiley

Subject

Pharmacology (medical),Pharmaceutical Science

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/cpdd.318/fullpdf

Reference37 articles.

1. Global epidemiology of hepatitis B virus infection: new estimates of age-specific HBsAg seroprevalence and endemicity;Ott;Vaccine,2012

2. Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010;Lozano;Lancet,2012

3. Hepatocellular carcinoma in cirrhosis: incidence and risk factors;Fattovich;Gastroenterology,2004

4. Natural history of hepatitis B;Marcellin;Minerva Gastroenterol Dietol,2005

5. EASL clinical practice guidelines: management of chronic hepatitis B virus infection;European Association For The Study Of The Liver;J Hepatol,2012

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