Assessment of Osteoarthritis Candidate Genes in a Meta‐Analysis of Nine Genome‐Wide Association Studies

Author:

Rodriguez‐Fontenla Cristina1,Calaza Manuel1,Evangelou Evangelos23,Valdes Ana M.3,Arden Nigel4,Blanco Francisco J.5,Carr Andrew4,Chapman Kay4,Deloukas Panos6,Doherty Michael7,Esko Tõnu8,Garcés Aletá Carlos M.9,Gomez‐Reino Carnota Juan J.10,Helgadottir Hafdis11,Hofman Albert12,Jonsdottir Ingileif11,Kerkhof Hanneke J. M.12,Kloppenburg Margreet13,McCaskie Andrew14,Ntzani Evangelia E.2,Ollier William E. R.15,Oreiro Natividad5,Panoutsopoulou Kalliope6,Ralston Stuart H.16,Ramos Yolande F.13,Riancho Jose A.9,Rivadeneira Fernando12,Slagboom P. Eline17,Styrkarsdottir Unnur11,Thorsteinsdottir Unnur11,Thorleifsson Gudmar11,Tsezou Aspasia18,Uitterlinden André G.12,Wallis Gillian A.19,Wilkinson J. Mark20,Zhai Guangju3,Zhu Yanyan21,Felson David T.21,Ioannidis John P. A.222,Loughlin John14,Metspalu Andres8,Meulenbelt Ingrid17,Stefansson Kari11,Meurs Joyce B.12,Zeggini Eleftheria6,Spector Timothy D.3,Gonzalez Antonio1,

Affiliation:

1. Hospital Clinico Universitario de SantiagoSantiago de CompostelaSpain

2. University of Ioannina School of MedicineIoanninaGreece

3. King's College LondonLondonUK

4. University of OxfordOxfordUK

5. Instituto de Investigacíon Biomédica–Complejo Hospitalario Universitario A CorunaA CorunaSpain

6. Wellcome Trust Sanger InstituteHinxton, CambridgeUK

7. Nottingham City HospitalNottinghamUK

8. University of TartuTartuEstonia

9. University of CantabriaSantanderSpain

10. Hospital Clinico Universitario de Santiago and University of Santiago de CompostelaSantiago de CompostelaSpain

11. deCODE GeneticsReykjavikIceland

12. Erasmus Medical Center and The Netherlands Genomics Initiative–Sponsored Netherlands Consortium for Healthy AgingRotterdamThe Netherlands

13. Leiden University Medical CentreLeidenThe Netherlands

14. Institute of Cellular Medicine, Newcastle UniversityNewcastle upon TyneUK

15. Centre for Integrated Genomic Medical Research, University of ManchesterManchesterUK

16. Institute of Genetics and Molecular Medicine, University of EdinburghEdinburghUK

17. Leiden University Medical Center, Leiden, The Netherlands, and The Netherlands Genomics Initiative–Sponsored Netherlands Consortium for Healthy AgingRotterdamThe Netherlands

18. University of ThessalyLarissaGreece

19. Wellcome Trust Centre for Cell‐Matrix Research, University of ManchesterManchesterUK

20. University of SheffieldSheffieldUK

21. Boston University School of MedicineBostonMA

22. Stanford University School of MedicineStanfordCA

Funder

European Union Seventh Framework Programme

Instituto de Salud Carlos III, Spain (ISCIII)

European Union

European Regional Development Fund

Instituto de Salud Carlos III, Spain (ISCIII predoctoral contract)

Xunta of Galicia, Spain (Isabel Barreto Program award)

Wellcome Trust

Instituto de Salud Carlos III, Spain

NWO (NWO Investments)

Research Institute for Diseases in the Elderly

The Netherlands Genomics Initiative/NWO

Erasmus Medical Center and Erasmus University, Rotterdam

Leiden University Medical Centre

Dutch Arthritis Association

Pfizer Inc., Groton, Connecticut

NWO

Leiden University Medical Center

Center of Medical System Biology

Netherlands Consortium of Healthy Aging in the framework of the Netherlands Genomics Initiative

The arcOGEN Phase I study (http://www.arcogen.org.uk/) was funded by Arthritis Research UK

Estonian government

Centre of Excellence in Genomics (EXCEGEN)

University of Tartu (SP1GVARENG)

Publisher

Wiley

Subject

Immunology,Rheumatology,Immunology and Allergy

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