A genetic variant nearGATA3implicated in inherited susceptibility and etiology of benign prostatic hyperplasia (BPH) and lower urinary tract symptoms (LUTS)

Author:

Na Rong123,Helfand Brian T.14,Chen Haitao5,Conran Carly A.1,Crawford Susan E.1,Hayward Simon W.1,Tammela Teuvo L.J.6,Hoffman-Bolton Judy7,Zheng Siqun L.1,Walsh Patrick C.8,Schleutker Johanna9,Platz Elizabeth A.7,Isaacs William B.810,Xu Jianfeng12ORCID

Affiliation:

1. Program for Personalized Cancer Care; NorthShore University HealthSystem; Evanston Illinois

2. Fudan Institute of Urology, Huashan Hospital; Fudan University; Shanghai China

3. Fudan Universtiy Shanghai Medical College; Shanghai; China

4. Department of Surgery; NorthShore University HealthSystem; Evanston Illinois

5. Fudan University School of Public Health; Shanghai; China

6. Department of Urology, Tampere University Hospital and Medical School; University of Tampere; Tampere Finland

7. Department of Epidemiology; Johns Hopkins University Bloomberg School of Public Health; Baltimore Maryland

8. Department of Urology and the James Buchanan Brady Urologic Institute; Johns Hopkins University School of Medicine; Baltimore Maryland

9. Department of Medical Biochemistry and Genetics; University of Turku; Turku Finland

10. Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins; Baltimore Maryland

Funder

GlaxoSmithKline

National Institute of Diabetes and Digestive and Kidney Diseases

National Cancer Institute

Publisher

Wiley

Subject

Urology,Oncology

Reference30 articles.

1. Epidemiology and natural history of benign prostatic hyperplasia;Barry;Urol Clin North Am,1990

2. The economics of medical therapy for lower urinary tract symptoms associated with benign prostatic hyperplasia;Nickel;Curr Urol Rep,2006

3. The pathogenesis of benign prostatic hyperplasia;Wilson;Am J Med,1980

4. Metabolic factors associated with benign prostatic hyperplasia;Parsons;J Clin Endocrinol Metab,2006

5. PPARγ: a molecular link between systemic metabolic disease and benign prostate hyperplasia;Jiang;Differentiation,2011

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