Pharmacokinetics and Pharmacodynamics of Anacetrapib in Black and White Healthy Subjects

Author:

Krishna Rajesh1,Gheyas Ferdous1,Corr Christy12,Cote Josee1,Liu Yang1,Wagner John13,Gutstein David E.14

Affiliation:

1. MRL, Merck & Co, Inc; Kenilworth NJ USA

2. BCH Research Solutions; LLC; West Chester PA USA

3. Takeda Pharmaceuticals International Co; Cambridge MA USA

4. Janssen Research & Development; LLC; Raritan NJ USA

Funder

Merck

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Reference23 articles.

1. Effect of anacetrapib on atheroschlerotic vascular disease;Bowman;N Engl J Med,2017

2. Merck & Co. Inc, press release: Merck provides update on anacetrapib development program. http://investors.merck.com/news/press-release-details/2017/Merck-Provides-Update-on-Anacetrapib-Development-Program/default.aspx 2018

3. Biochemical characterization of cholesteryl ester transfer protein inhibitors;Ranalletta;J Lipid Res,2010

4. O'Neil E Sparrow CP Chen Y Identification and characterization of anacetrapib (MK-0859): a novel CETP inhibitor.Presented at: XVI International Symposium on Drugs Affecting Lipid Metabolism . New York, 4-7 October 2007

5. Single-dose pharmacokinetics and pharmacodynamics of anacetrapib, a potent cholesteryl ester transfer protein (CETP) inhibitor, in healthy subjects;Krishna;Br J Clin Pharmacol,2009

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