Prevalence of dementia in India: National and state estimates from a nationwide study

Author:

Lee Jinkook12ORCID,Meijer Erik1,Langa Kenneth M.345,Ganguli Mary6,Varghese Mathew7,Banerjee Joyita8,Khobragade Pranali1,Angrisani Marco12,Kurup Ravi9,Chakrabarti Sankha Shubhra10,Gambhir Indrajeet Singh10,Koul Parvaiz A.11,Goswami Debabrata12,Talukdar Arunanshu13,Mohanty Rashmi Ranjan14,Yadati Raju Sathyanarayana15,Padmaja Mekala15,Sankhe Lalit16,Rajguru Chhaya16,Gupta Monica17,Kumar Govind18,Dhar Minakshi19,Chatterjee Prasun8,Singhal Sunny8,Bansal Rishav8,Bajpai Swati8,Desai Gaurav8,Rao Abhijith R.8,Sivakumar Palanimuthu T.7,Muliyala Krishna Prasad7,Bhatankar Swaroop20,Chattopadhyay Aparajita21,Govil Dipti21,Pedgaonkar Sarang21,Sekher T. V.21,Bloom David E.22,Crimmins Eileen M.23,Dey Aparajit Ballav8

Affiliation:

1. Center for Economic and Social Research University of Southern California Los Angeles California USA

2. Department of Economics University of Southern California Los Angeles California USA

3. Department of Internal Medicine University of Michigan Ann Arbor Michigan USA

4. Center for Clinical Management Research Veterans Affairs Ann Arbor Michigan USA

5. Institute for Social Research University of Michigan Ann Arbor Michigan USA

6. Department of Psychiatry University of Pittsburgh Pittsburgh Pennsylvania USA

7. Department of Psychiatry National Institute of Mental Health and Neurosciences Bengaluru India

8. Department of Geriatric Medicine All India Institute of Medical Sciences New Delhi India

9. Department of Medicine Government Medical College Thiruvananthapuram India

10. Department of Geriatric Medicine Institute of Medical Sciences Banaras Hindu University Varanasi India

11. Department of Internal and Pulmonary Medicine Sher‐e‐Kashmir Institute of Medical Sciences Srinagar India

12. Department of Medicine Guwahati Medical College Guwahati India

13. Department of Geriatric Medicine Medical College Kolkata India

14. Department of Medicine All India Institute of Medical Sciences Bhubaneshwar India

15. Department of Medicine Nizam's Institute of Medical Sciences Hyderabad India

16. Department of Community Medicine Grant Medical College and J.J. Hospital Mumbai India

17. Department of General Medicine Government Medical College and Hospital Chandigarh India

18. Department of Medicine Indira Gandhi Institute of Medical Science Patna India

19. Department of Medicine All India Institute of Medical Sciences Rishikesh India

20. Institute of the Psychological Health Mumbai India

21. International Institute for Population Sciences Mumbai India

22. Department of Global Health and Population Harvard T.H. Chan School of Public Health Boston Massachusetts USA

23. School of Gerontology University of Southern California Los Angeles California USA

Abstract

AbstractIntroductionPrior estimates of dementia prevalence in India were based on samples from selected communities, inadequately representing the national and state populations.MethodsFrom the Longitudinal Aging Study in India (LASI) we recruited a sample of adults ages 60+ and administered a rich battery of neuropsychological tests and an informant interview in 2018 through 2020. We obtained a clinical consensus rating of dementia status for a subsample (N = 2528), fitted a logistic model for dementia status on this subsample, and then imputed dementia status for all other LASI respondents aged 60+ (N = 28,949).ResultsThe estimated dementia prevalence for adults ages 60+ in India is 7.4%, with significant age and education gradients, sex and urban/rural differences, and cross‐state variation.DiscussionAn estimated 8.8 million Indians older than 60 years have dementia. The burden of dementia cases is unevenly distributed across states and subpopulations and may therefore require different levels of local planning and support.Highlights The estimated dementia prevalence for adults ages 60+ in India is 7.4%. About 8.8 million Indians older than 60 years live with dementia. Dementia is more prevalent among females than males and in rural than urban areas. Significant cross‐state variation exists in dementia prevalence.

Publisher

Wiley

Subject

Psychiatry and Mental health,Cellular and Molecular Neuroscience,Geriatrics and Gerontology,Neurology (clinical),Developmental Neuroscience,Health Policy,Epidemiology

Reference54 articles.

1. United Nations Department of Economic and Social Affairs Population Division.World Population Prospects 2022: Summary of Results. UN DESA/POP/2022/TR/NO.3. New York: United Nations New York

2. 2022. Accessed September 3 2020.https://www.un.org/development/desa/pd/content/World‐Population‐Prospects‐2022

3. World Population Ageing 2019

4. Epidemiology and risk factors of dementia

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