A phase II clinical study of 13‐deoxy, 5‐iminodoxorubicin (GPX‐150) with metastatic and unresectable soft tissue sarcoma

Author:

Van Tine Brian A.1ORCID,Agulnik Mark2,Olson Richard D.3,Walsh Gerald M.3,Klausner Arthur3,Frank Nicole E.4,Talley Todd T.4,Milhem Mohammed M.5

Affiliation:

1. Division of Medical Oncology Washington University in St. Louis St Louis Missouri

2. Division of Hematology/Oncology, Feinberg School of Medicine Northwestern University Chicago Illinois

3. Gem Pharmaceuticals LLC Birmingham Alabama

4. College of Pharmacy Idaho State University Meridian Idaho

5. Division of Hematology/Oncology University of Iowa Hospitals and Clinics Iowa City Iowa

Funder

Gem Pharmaceuticals LLC

Publisher

Wiley

Subject

Cancer Research,Radiology Nuclear Medicine and imaging,Oncology

Reference33 articles.

1. Doxorubicin alone versus intensified doxorubicin plus ifosfamide for first-line treatment of advanced or metastatic soft-tissue sarcoma: a randomised controlled phase 3 trial

2. Adriamycin cardiomyopathy—risk factors

3. Phase II evaluation of adriamycin in human neoplasia

4. The Anthracycline Antineoplastic Drugs

5. A randomized phase Ib/II study evaluating the safety and efficacy of olaratumab (IMC‐3G3), a human anti‐platelet‐derived growth factor α (PDGFRα) monoclonal antibody, with or without doxorubicin (Dox), in advanced soft tissue sarcoma (STS);Tap WD;J Clin Oncol,2015

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