Efficient bioconversion of daptomycin to its nucleus by heterologous expression of deacylase genes in Streptomyces

Author:

Wang Xiaojing12ORCID,Liu Jing13,Zhang Hanzhi4,Wu Kai12,Yang Zhijun12,Ning Ruonan12,Huang Junhai5,Shao Lei125ORCID

Affiliation:

1. Microbial Pharmacology Laboratory Shanghai University of Medicine and Health Sciences Shanghai China

2. School of Pharmacy Shanghai University of Medicine and Health Sciences Shanghai China

3. School of Medical Technology Shanghai University of Medicine and Health Sciences Shanghai China

4. Department of Antibiotics and Microorganisms Shanghai Institute for Food and Drug Control Shanghai China

5. State Key Laboratory of New Drug and Pharmaceutical Process, Shanghai Institute of Pharmaceutical Industry China State Institute of Pharmaceutical Industry Shanghai China

Funder

National Natural Science Foundation of China

Natural Science Foundation of Shanghai

Publisher

Wiley

Subject

Inorganic Chemistry,Organic Chemistry,Pollution,Waste Management and Disposal,Fuel Technology,Renewable Energy, Sustainability and the Environment,General Chemical Engineering,Biotechnology

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