1. School of Cancer Sciences, Faculty of Medicine University of Southampton Southampton UK
2. Integrative Physiology and Critical Illness Group, Clinical and Experimental Sciences, Faculty of Medicine University of Southampton Southampton UK
3. Anaesthesia, Perioperative, and Critical Care Research Group, Southampton NIHR Biomedical Research Centre University Hospital Southampton NHS Foundation Trust Southampton UK
4. Department of Upper Gastro‐intestinal Surgery University Hospital Southampton NHS Foundation Trust Southampton UK