Interaction between a haptoglobin genetic variant and coronary artery disease (CAD) risk factors on CAD severity in Singaporean Chinese population

Author:

Chang Xuling12,Dorajoo Rajkumar3,Han Yi4,Wang Ling3,Liu Jianjun35,Khor Chiea‐Chuen36,Low Adrian F.57,Chan Mark Yan‐Yee5,Yuan Jian‐Min89,Koh Woon‐Puay1011,Friedlander Yechiel12,Heng Chew‐Kiat12ORCID

Affiliation:

1. Department of Paediatrics Yong Loo Lin School of Medicine National University of Singapore Singapore Singapore

2. Khoo Teck Puat – National University Children’s Medical Institute National University Health System Singapore Singapore

3. Genome Institute of SingaporeAgency for Science, Technology and Research Singapore Singapore

4. Departments of Preventive Medicine and Biochemistry & Molecular Medicine Keck School of Medicine University of Southern California Los Angeles CA USA

5. Department of Medicine Yong Loo Lin School of Medicine National University of Singapore Singapore Singapore

6. Singapore Eye Research InstituteSingapore National Eye Centre Singapore Singapore

7. National University Heart CentreNational University Health System Singapore Singapore

8. Division of Cancer Control and Population Sciences UPMC Hillman Cancer CenterUniversity of Pittsburgh Pittsburgh PA USA

9. Department of Epidemiology Graduate School of Public Health University of Pittsburgh Pittsburgh PA USA

10. Saw Swee Hock School of Public Health National University of Singapore Singapore Singapore

11. Health Systems and Services Research Duke‐NUS Medical School Singapore Singapore Singapore

12. School of Public Health and Community Medicine Hebrew University of Jerusalem Jerusalem Israel

Funder

National Institutes of Health

National Research Foundation Singapore

Publisher

Wiley

Subject

Genetics(clinical),Genetics,Molecular Biology

Reference47 articles.

1. Genetically Determined Heterogeneity in Hemoglobin Scavenging and Susceptibility to Diabetic Cardiovascular Disease

2. Recurring exon deletions in the HP (haptoglobin) gene contribute to lower blood cholesterol levels;Boettger L. M.;Nature Genetics,2015

3. CDC.International Classification of Diseases. 9th revision. Retrieved fromhttps://www.cdc.gov/nchs/icd/icd9cm.htm

4. CDC.International Classification of Diseases. 10th revision. Retrieved fromhttps://www.cdc.gov/nchs/icd/icd10.htm

5. Utility of genetic and non-genetic risk factors in predicting coronary heart disease in Singaporean Chinese

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