Quantitative single‐molecule imaging of TNFR1 reveals zafirlukast as antagonist of TNFR1 clustering and TNFα‐induced NF‐ĸB signaling

Author:

Weinelt Nadine1ORCID,Karathanasis Christos2ORCID,Smith Sonja1ORCID,Medler Juliane3ORCID,Malkusch Sebastian4ORCID,Fulda Simone156ORCID,Wajant Harald3ORCID,Heilemann Mike2ORCID,Wijk Sjoerd J. L.1ORCID

Affiliation:

1. Institute for Experimental Cancer Research in Pediatrics Goethe University Frankfurt am Main Germany

2. Institute of Physical and Theoretical Chemistry Goethe University Frankfurt am Main Germany

3. Division of Molecular Internal Medicine, Department of Internal Medicine II University Hospital Würzburg Auverahaus Würzburg Germany

4. Institute of Clinical Pharmacology Goethe‐University Frankfurt am Main Germany

5. German Cancer Consortium (DKTK) Partner site Frankfurt am Main Germany

6. German Cancer Research Centre (DKFZ) Heidelberg Germany

Funder

Deutsche Forschungsgemeinschaft

Publisher

Wiley

Subject

Cell Biology,Immunology,Immunology and Allergy

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