Differential pharmacokinetic analysis ofin vivoerythropoietin receptor interaction with erythropoietin and continuous erythropoietin receptor activator in sheep

Author:

El-Komy Mohammed H.1,Schmidt Robert L.2,Widness John A.2,Veng-Pedersen Peter1

Affiliation:

1. Division of Pharmaceutics, College of Pharmacy; The University of Iowa; Iowa City IA USA

2. Department of Pediatrics, College of Medicine; The University of Iowa; Iowa City IA USA

Funder

Roche Penzberg Germany

Publisher

Wiley

Subject

Pharmacology (medical),Pharmaceutical Science,Pharmacology,General Medicine

Reference42 articles.

1. Maintenance by erythropoietin of viability and maturation of murine erythroid precursor cells;Koury;J Cell Physiol,1988

2. The molecular biology of erythropoietin;Lacombe;Nephrol Dial Transplant,1999

3. Erythropoietin receptor activation by a ligand-induced conformation change;Remy;Science,1999

4. Both proteasomes and lysosomes degrade the activated erythropoietin receptor;Walrafen;Blood,2005

5. Mechanism for the nonlinear pharmacokinetics of erythropoietin in rats;Kato;J Pharmacol Exp Ther,1997

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