Purification of a conjugated polysaccharide vaccine using tangential flow diafiltration
Author:
Affiliation:
1. Department of Chemical EngineeringThe Pennsylvania State UniversityUniversity Park Pennsylvania
2. Biotherapeutics Pharmaceutical SciencesPfizer IncAndover Massachusetts
Funder
Pfizer
Publisher
Wiley
Subject
Applied Microbiology and Biotechnology,Bioengineering,Biotechnology
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1002/bit.26867
Reference22 articles.
1. Anderson P. W. & Eby R. J. (1990).Immunogenic conjugates. US4902506A.
2. Molecular size analysis of capsular polysaccharide preparations from Streptococcus pneumoniae
3. Streptococcus pneumoniae colonisation: the key to pneumococcal disease
4. Impact of module geometry on the ultrafiltration behavior of capsular polysaccharides for vaccines
5. Development and clinical evaluation of Prevnar 13, a 13-valent pneumocococcal CRM197 conjugate vaccine
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