3-Amino-1H-pyrazolopyridine Derivatives as a Maternal Embryonic Leucine Zipper Kinase Inhibitor-Reference-Cited by-同舟云学术

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3-Amino-1H-pyrazolopyridine Derivatives as a Maternal Embryonic Leucine Zipper Kinase Inhibitor

Published:2017-05-25 Issue:6 Volume:38 Page:595-602
ISSN:1229-5949
Container-title:Bulletin of the Korean Chemical Society
language:en
Short-container-title:Bull. Korean Chem. Soc.

Author:

Park Chul Min¹,Jadhav Vithal B.¹,Song Jong-Hwan¹,Lee Sunkyung¹²,Won Hee Young¹²,Choi Sang Un¹,Son You Hwa¹

Affiliation:

1. Division of Drug Discovery Research; Korea Research Institute of Chemical Technology; Deajeon 305-600 Korea

2. Department of medicinal Chemistry and Pharmacology, Korea University of Science and Technology; Daejeon 305-343 Korea

Funder

National Research Council of Science & Technology (NST)

Technology Innovation Program

Korea Evaluation Institute of Industrial Technology

Ministry of Trade, Industry & Energy, Republic of Korea

Publisher

Wiley

Subject

General Chemistry

Reference19 articles.

1. Maternal Embryonic Leucine Zipper Kinase (MELK) Reduces Replication Stress in Glioblastoma Cells

2. Maternal Embryonic Leucine Zipper Kinase/Murine Protein Serine-Threonine Kinase 38 Is a Promising Therapeutic Target for Multiple Cancers

3. Development of an orally-administrative MELK-targeting inhibitor that suppresses the growth of various types of human cancer

4. Molecular features of triple negative breast cancer cells by genome-wide gene expression profiling analysis

5. Preclinical efficacy of maternal embryonic leucine-zipper kinase (MELK) inhibition in acute myeloid leukemia

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1. Pyrazolopyridine: An efficient pharmacophore in recent drug design and development;Chemical Biology & Drug Design;2022-06-16

2. Bicyclic 5-6 Systems: Three Heteroatoms 2:1;Comprehensive Heterocyclic Chemistry IV;2022

3. Synthesis and Antiproliferative Activity of 2,4,6,7-Tetrasubstituted-2H-pyrazolo[4,3-c]pyridines;Molecules;2021-11-08

4. Crystal structure analysis of ethyl 6-(4-methoxyphenyl)-1-methyl-4-methylsulfanyl-3-phenyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylate;Acta Crystallographica Section E Crystallographic Communications;2020-07-07

5. Design and Synthesis of New Substituted Pyrazolopyridines with Potent Antiproliferative Activity;Medicinal Chemistry;2020-02-20

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