A Possible Antineoplastic Potential of Selective, Irreversible Proteasome Inhibitor, Carfilzomib on Chemically Induced Hepatocarcinogenesis in Rats-Reference-Cited by-同舟云学术

A Possible Antineoplastic Potential of Selective, Irreversible Proteasome Inhibitor, Carfilzomib on Chemically Induced Hepatocarcinogenesis in Rats

Published:2014-05-27 Issue:9 Volume:28 Page:400-406
ISSN:1095-6670
Container-title:Journal of Biochemical and Molecular Toxicology
language:en
Short-container-title:J Biochem Mol Toxicol

Author:

Mansour Mahmoud A.¹,Aljoufi Mohammed A.²,Al-Hosaini Khaled²,Al-Rikabi Ammar C.³,Nagi Mahmoud N.²

Affiliation:

1. Department of Basic Pharmaceutical Sciences; College of Pharmacy; King Saud bin Abdulaziz University for Health Sciences; Riyadh 11426 Saudi Arabia

2. Department of Pharmacology; College of Pharmacy; King Saud University; Riyadh 11451 Saudi Arabia

3. Department of Pathology; College of Medicine; King Saud University; Riyadh 11461 Saudi Arabia

Publisher

Wiley

Subject

Health, Toxicology and Mutagenesis,Toxicology,Molecular Biology,Molecular Medicine,Biochemistry,General Medicine

Reference34 articles.

1. Proteasome inhibitors in cancer therapy: lessons from the first decade;Orlowski;Clin Cancer Res,2008

2. A subcomplex of the proteasome regulatory particle required for ubiquitin-conjugate degradation and related to the Cop9-signalosome and eIF3;Glickman;Cell,1998

3. Antitumor activity of Pr-171, A novel irreversible inhibitor of the proteasome;Demo;Cancer Res,2007

4. An open-label, single-arm, phase 2 (Px-171-004) study of single-agent carfilzomib in bortezomib-naive patients with relapsed and/or refractory multiple myeloma;Vij;Blood,2012

5. Pharmacokinetics, pharmacodynamics, metabolism, distribution, and excretion of carfilzomib in rats;Yang;Drug Metab Dispos,2011

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