Adverse Cardiovascular Outcomes and Antihypertensive Treatment: A Genome‐Wide Interaction Meta‐Analysis in the International Consortium for Antihypertensive Pharmacogenomics Studies

Author:

McDonough Caitrin W.1,Warren Helen R.23,Jack John R.4,Motsinger‐Reif Alison A.5,Armstrong Nicole D.6,Bis Joshua C.7,House John S.5,Singh Sonal1,El Rouby Nihal M.1,Gong Yan1,Mychaleckyj Joesyf C.8,Rotroff Daniel M.4,Benavente Oscar R.9,Caulfield Mark J.10,Doria Alessandrio11,Pepine Carl J.12,Psaty Bruce M.713,Glorioso Valeria14,Glorioso Nicola15,Hiltunen Timo P.16,Kontula Kimmo K.16,Arnett Donna K.17,Buse John B.18,Irvin Marguerite R.6,Johnson Julie A.112,Munroe Patricia B.23,Wagner Michael J.19,Cooper‐DeHoff Rhonda M.112

Affiliation:

1. Department of Pharmacotherapy and Translational Research and Center for Pharmacogenomics and Precision Medicine College of Pharmacy University of Florida Gainesville Florida USA

2. Clinical Pharmacology Department William Harvey Research InstituteBarts and The London School of Medicine and DentistryQueen Mary University of London London UK

3. NIHR Cardiovascular Biomedical Research Centre Barts and The London School of Medicine and Dentistry Queen Mary University of London London UK

4. Bioinformatics Research Center Department of Statistics North Carolina State University Raleigh North Carolina USA

5. Biostatistics and Computational Biology Branch National Institute of Environmental Health Sciences Durham North Carolina USA

6. Department of Epidemiology University of Alabama at Birmingham Birmingham Alabama USA

7. Cardiovascular Health Research Unit Department of Medicine University of Washington Seattle Washington USA

8. Center for Public Health Genomics University of Virginia Charlottesville Virginia USA

9. Department of Neurology University of British Columbia Vancouver British Columbia Canada

10. National Institute for Health Research Barts Cardiovascular Biomedical Research CenterQueen Mary University of London London UK

11. Research Division Joslin Diabetes Center; and Department of Medicine Harvard Medical School Boston Massachusetts USA

12. Division of Cardiovascular Medicine Department of Medicine College of Medicine University of Florida Gainesville Florida USA

13. Department of Epidemiology University of Washington Seattle Washington USA

14. Department of Statistics and Quantitative Methods University of Milano‐Bicocca Milano Italy

15. Department of Clinical Surgical and Experimental Science University of SassariMedical School Sassari Italy

16. Department of Medicine and Research Program for Clinical and Molecular Metabolism University of Helsinki and Helsinki University Hospital Helsinki Finland

17. College of Public Health Dean’s Office University of Kentucky Lexington Kentucky USA

18. Division of Endocrinology Department of Medicine UNC School of MedicineUniversity of North Carolina at Chapel Hill Chapel Hill North Carolina USA

19. Center for Pharmacogenomics and Individualized Therapy University of North Carolina at Chapel Hill Chapel Hill North Carolina USA

Funder

National Institutes of Health

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

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