Advances in two‐dimensional transition metal dichalcogenides‐based sensors for environmental, food, and biomedical analysis: A review

Author:

Raghunathan Muthukumar1,Kapoor Ashish2ORCID,Mohammad Akbar3,Kumar Praveen1,Singh Rajeev4,Tripathi Subhash C.5,Muzammil Khursheed6,Pal Dan Bahadur2ORCID

Affiliation:

1. Department of Biotechnology, School of Bioengineering SRM Institute of Science and Technology, Kattankulathur Chennai Tamil Nadu India

2. Department of Chemical Engineering Harcourt Butler Technical University Kanpur Uttar Pradesh India

3. School of Chemical Engineering Yeungnam University Gyeongsan Gyeongsangbuk‐do Republic of Korea

4. Department of Chemical Environmental Science Jamia Millia Islamia New Delhi India

5. Institute of Applied Sciences & Humanities, Department of Chemistry GLA University Mathura Uttar Pradesh India

6. Department of Public Health College of Applied Medical Sciences, Khamis Mushait Campus King Khalid University Abha Saudi Arabia

Abstract

AbstractTransition metal dichalcogenides (TMDCs) are versatile two‐dimensional (2D) nanomaterials used in biosensing applications due to their excellent physical and chemical properties. Due to biomaterial target properties, biosensors' most significant challenge is improving their sensitivity and stability. In environmental analysis, TMDCs have demonstrated exceptional pollutant detection and removal capabilities. Their high surface area, tunable electronic properties, and chemical reactivity make them ideal for sensors and adsorbents targeting various contaminants, including heavy metals, organic pollutants, and emerging contaminants. Furthermore, their unique electronic and optical properties enable sensitive detection techniques, enhancing our ability to monitor and mitigate environmental pollution. In the food analysis, TMDCs‐based nanomaterials have shown remarkable potential in ensuring food safety and quality. These nanomaterials exhibit high specificity and sensitivity for detecting contaminants, pathogens, and adulterants in various food matrices. Their integration into sensor platforms enables rapid and on‐site analysis, reducing the reliance on centralized laboratories and facilitating timely interventions in the food supply chain. In biomedical studies, TMDCs‐based nanomaterials have demonstrated significant strides in diagnostic and therapeutic applications. Their biocompatibility, surface functionalization versatility, and photothermal properties have paved the way for novel disease detection, drug delivery, and targeted therapy approaches. Moreover, TMDCs‐based nanomaterials have shown promise in imaging modalities, providing enhanced contrast and resolution for various medical imaging techniques. This article provides a comprehensive overview of 2D TMDCs‐based biosensors, emphasizing the growing demand for advanced sensing technologies in environmental, food, and biomedical analysis.

Publisher

Wiley

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