Fermentation and purification strategies for the production of betulinic acid and its lupane-type precursors in Saccharomyces cerevisiae

Author:

Czarnotta Eik1,Dianat Mariam1,Korf Marcel2,Granica Fabian2,Merz Juliane2ORCID,Maury Jérôme3,Baallal Jacobsen Simo A.3,Förster Jochen3,Ebert Birgitta E.1ORCID,Blank Lars M.1

Affiliation:

1. iAMB-Institute of Applied Microbiology; ABBt-Aachen Biology and Biotechnology; RWTH Aachen University; Aachen Germany

2. APT-Laboratory of Plant and Process Design; Department of Biochemical and Chemical Engineering; TU Dortmund University; Dortmund Germany

3. Technical University of Denmark; Novo Nordisk Foundation Center for Biosustainability; Kgs. Lyngby Denmark

Funder

Deutsche Bundesstiftung Umwelt

Publisher

Wiley

Subject

Applied Microbiology and Biotechnology,Bioengineering,Biotechnology

Reference53 articles.

1. Influence of growth rate on the accumulation of ergosterol in yeast-cells;Arnezeder;Biotechnology Letters,1990

2. A standard procedure for the selection of solvents for natural plant extraction in the early stages of process development;Bergs;Chemical Engineering and Technology,2013

3. Redox biocatalysis and metabolism: Molecular mechanisms and metabolic network analysis;Blank;Antioxidants Redox Signaling,2010

4. Profiling of cytosolic and peroxisomal acetyl-CoA metabolism in Saccharomyces cerevisiae;Chen;PLoS ONE,2012

5. Solubilities of betulinic acid in thirteen organic solvents at different temperatures;Cheng;Journal of Chemical and Engineering Data,2011

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