A novel and fully validated hydrophilic interaction liquid chromatography with tandem mass spectrometry method for the determination of intact carboplatin in human plasma

Author:

Ren Guanghui1,Qin Zhiying1,Fan Ali1,Wang Yonghan1,Tan Yanan1,Lu Yang1,Li Ning2,Chen Xijng1ORCID,Zhao Di1

Affiliation:

1. Clinical Pharmacokinetics Laboratory; China Pharmaceutical University; Nanjing Jiangsu Province China

2. Center of Drug Metabolism and Pharmacokinetics; China Pharmaceutical University; Nanjing Jiangsu Province China

Funder

National Natural Science Foundation of China

Publisher

Wiley

Reference28 articles.

1. Paclitaxel enhances carboplatin-DNA adduct formation and cytotoxicity;Jiang;Chem. Res. Toxicol.,2015

2. Therapy-induced carboplatin-DNA adduct levels in human ovarian tumours in relation to assessment of adduct measurement in mouse tissues;Jarvis;Biochem. Pharmacol.,2012

3. Comparison of two methods for carboplatin dosing in children with retinoblastoma;Allen;Pediatr. Blood Cancer,2010

4. Analytical approaches to investigating metal-containing drugs;Harrington;J. Pharm. Biomed. Anal.,2015

5. Platinum-based drugs and proteins: Reactivity and relevance to DNA adduct formation;Pinato;J. Inorg. Biochem.,2013

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