Design and optimization of a reversed-phase HPLC with diode array detection method for the determination of acemetacin and its toxic impurities using experimental design

Author:

Abdelgawad Mohamed A.12,Owis Asmaa I.3,Abdelwahab Nada S.4

Affiliation:

1. Pharmaceutical Organic Chemistry, Faculty of Pharmacy; Beni-suef University; Beni-suef Egypt

2. Pharmaceutical Chemistry, College of Pharmacy; Jouf University; Aljouf KSA

3. Pharmacognosy, Faculty of Pharmacy; Beni-suef University; Beni-suef Egypt

4. Pharmaceutical Analytical Chemistry, Faculty of Pharmacy; Beni-Suef University; Beni-Suef Egypt

Publisher

Wiley

Reference25 articles.

1. Development and validation of stability indicating spectrophotometric and HPTLC methods for determination of acemetacin;Naguib;European J. Chem.,2014

2. Pharmacokinetics of Indomethacin, a metabolite of acemetacin, following a single dose and Multiple doses administered as Acemetacin sustained release tablets in healthy male volunteers;Li;Health Sci.,2005

3. Micellar liquid chromatography and derivative spectrophotometry for the simultaneous determination of acemetacin and chlorzoxazone in their tablets and human plasma;Walash;Sep. Sci.Technol.,2015

4. 2012

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