Development and application of a pediatric mechanistic kidney model
Author:
Affiliation:
1. Drug Metabolism and Pharmacokinetics GlaxoSmithKline R&D Ware UK
2. Simcyp Division Certara UK Limited Sheffield UK
Publisher
Wiley
Subject
Pharmacology (medical),Modeling and Simulation
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1002/psp4.12798
Reference59 articles.
1. Simultaneous Pharmacokinetic Modeling of Gentamicin, Tobramycin and Vancomycin Clearance from Neonates to Adults: Towards a Semi-physiological Function for Maturation in Glomerular Filtration
2. Maturation and growth of renal function: Dosing renally cleared drugs in children
3. Prediction of the Clearance of Eleven Drugs and Associated Variability in Neonates, Infants and Children
4. Human renal function maturation: a quantitative description using weight and postmenstrual age
5. The Predictive Value of Glomerular Filtration Rate-Based Scaling of Pediatric Clearance and Doses for Drugs Eliminated by Glomerular Filtration with Varying Protein-Binding Properties
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