Population pharmacokinetic modeling of GS‐441524, the active metabolite of remdesivir, in Japanese COVID‐19 patients with renal dysfunction

Author:

Sukeishi Asami1,Itohara Kotaro1,Yonezawa Atsushi12,Sato Yuki1,Matsumura Katsuyuki1,Katada Yoshiki1,Nakagawa Takayuki1,Hamada Satoshi3,Tanabe Naoya3,Imoto Eishi4,Kai Shinichi5,Hirai Toyohiro3,Yanagita Motoko67,Ohtsuru Shigeru8,Terada Tomohiro1,Ito Isao3

Affiliation:

1. Department of Clinical Pharmacology and Therapeutics Kyoto University Hospital Kyoto Japan

2. Graduate School of Pharmaceutical Sciences Kyoto University Kyoto Japan

3. Department of Respiratory Medicine Graduate School of Medicine Kyoto University Kyoto Japan

4. Shimadzu Corporation Kyoto Japan

5. Department of Anesthesia Kyoto University Hospital Kyoto Japan

6. Department of Nephrology Graduate School of Medicine Kyoto University Kyoto Japan

7. Institute for the Advanced Study of Human Biology (WPI‐ASHBi) Kyoto University Kyoto Japan

8. Department of Primary Care and Emergency Medicine Graduate School of Medicine Kyoto University Kyoto Japan

Funder

Kyoto University

Publisher

Wiley

Subject

Pharmacology (medical),Modeling and Simulation

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