Pitfalls in genetic testing: a case of a SNP in primer-annealing region leading to allele dropout in BRCA1
Author:
Affiliation:
1. Laboratory of Genomics and Molecular Biology; International Research Center; AC Camargo Cancer Center; São Paulo Brazil
2. Genomic Diagnostics Laboratory; Anatomic Pathologic Department; AC Camargo Cancer Center; São Paulo Brazil
Funder
Fundação de Amparo à Pesquisa do Estado de São Paulo
Publisher
Wiley
Subject
Genetics(clinical),Genetics,Molecular Biology
Reference11 articles.
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3. Large-scale comparison of intron positions among animal, plant, and fungal genes;Fedorov;Proc. Natl. Acad. Sci. U S A,2002
4. Not all next generation sequencing diagnostics are created equal: understanding the nuances of solid tumor assay design for somatic mutation detection;Gray;Cancers,2015
5. Allele-specific PCR amplification due to sequence identity between a PCR primer and an amplicon: is direct sequencing so reliable?;Ikegawa;Hum. Genet.,2002
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