New NO-Donors with Antithrombotic and Vasodilating Activities, Part 16 3-Amino-1,2,4-oxadiazol-5-ones as Prodrugs for Hydroxyguanidines
Author:
Publisher
Wiley
Subject
Drug Discovery,Pharmaceutical Science
Reference16 articles.
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2. Cytochrome P450 dependent N-hydroxylation of a guanidine (debrisoquine), microsomal catalysed reduction and further oxidation of the N-hydroxy-guanidine metabolite to the urea derivative
3. Formation of nitric oxide by cytochrome P450-catalyzed oxidation of aromatic amidoximes
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1. 3-Amino-1,2,4(4H)-oxadiazol-5-one (AOD) and its nitrogen-rich salts: a class of insensitive energetic materials;New Journal of Chemistry;2018
2. Prodrug design for the potent cardiovascular agent Nω-hydroxy-l-arginine (NOHA): Synthetic approaches and physicochemical characterization;Organic & Biomolecular Chemistry;2011
3. ChemInform Abstract: New NO-Donors with Antithrombotic and Vasodilating Activities. Part 16. 3-Amino-1,2,4-oxadiazol-5-ones as Prodrugs for Hydroxyguanidines.;ChemInform;2010-08-03
4. Inhibition of secretory phospholipase A. 1-Design, synthesis and structure–activity relationship studies starting from 4-tetradecyloxybenzamidine to obtain specific inhibitors of group II sPLAs;European Journal of Medicinal Chemistry;2005-09
5. The NO-Releasing Heterocycles;Nitric Oxide Donors;2005-05-23
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