The histone demethylase UTX/KDM6A in cancer: Progress and puzzles
Author:
Affiliation:
1. Department of Urology, Medical Faculty; Heinrich Heine University Düsseldorf; Düsseldorf Germany
2. Department of Molecular Physical Chemistry; Heinrich Heine University Düsseldorf; Düsseldorf Germany
Funder
Strategischer Forschungsfond der Heinrich-Heine-Universität
Wilhelm Sander-Stiftung
Publisher
Wiley
Subject
Cancer Research,Oncology
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1002/ijc.32116/fullpdf
Reference64 articles.
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2. Somatic mutations of the histone H3K27 demethylase gene UTX in human cancer;Haaften;Nat Genet,2009
3. Frequent mutations of chromatin remodeling genes in transitional cell carcinoma of the bladder;Gui;Nat Genet,2011
4. UTX and MLL4 coordinately regulate transcriptional programs for cell proliferation and invasiveness in breast cancer cells;Kim;Cancer Res,2014
5. UTX promotes hormonally responsive breast carcinogenesis through feed-forward transcription regulation with estrogen receptor;Xie;Oncogene,2017
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