Is SARS‐CoV‐2 viral clearance in nasopharyngeal swabs an appropriate surrogate marker for clinical efficacy of neutralising antibody‐based therapeutics?

Author:

Focosi Daniele1ORCID,Franchini Massimo2,Pirofski Liise‐anne3,Maggi Fabrizio45,Casadevall Arturo6

Affiliation:

1. North‐Western Tuscany Blood Bank Pisa University Hospital Pisa Italy

2. Division of Transfusion Medicine Carlo Poma Hospital Mantua Italy

3. Division of Infectious Diseases Departments of Medicine, Microbiology and Immunology Albert Einstein College of Medicine and Montefiore Medical Center New York City New York USA

4. Department of Medicine and Surgery University of Insubria Varese Italy

5. Laboratory of Microbiology ASST Sette Laghi Varese Italy

6. Department of Medicine Johns Hopkins School of Public Health and School of Medicine Baltimore Maryland USA

Publisher

Wiley

Subject

Infectious Diseases,Virology

Reference104 articles.

1. Casirivimab and imdevimab in patients admitted to hospital with COVID‐19 (RECOVERY): a randomised, controlled, open‐label;Recovery Collaborative Group;medRxiv,2021

2. Bamlanivimab plus Etesevimab in Mild or Moderate Covid-19

3. Early Treatment for Covid-19 with SARS-CoV-2 Neutralizing Antibody Sotrovimab

4. Subcutaneous REGEN‐COV antibody combination to prevent Covid‐19;O’Brien MP;N Engl J Med,2021

5. REGN-COV2, a Neutralizing Antibody Cocktail, in Outpatients with Covid-19

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