Experimental and natural infections in MyD88- and IRAK-4-deficient mice and humans

Author:

von Bernuth Horst12,Picard Capucine345,Puel Anne45,Casanova Jean-Laurent4567

Affiliation:

1. Pediatric Pneumology and Immunology; Charité Hospital - Humboldt University; Berlin Germany

2. Labor Berlin Charité Vivantes GmbH; Fachbereich Immunologie; Berlin Germany

3. Study Center for Primary Immunodeficiencies; Assistance Publique Hôpitaux de Paris, Necker Hospital; Paris France

4. Laboratory of Human Genetics of Infectious Diseases, Necker Branch; Institut National de la Santé et de la Recherche Médicale (INSERM) U980; Necker Medical School; Paris France

5. University of Paris Descartes; Sorbonne Paris Cité; Paris France

6. St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch; The Rockefeller University, New York; NY USA

7. Pediatric Hematology-Immunology Unit; Necker Hospital; Assistance Publique Hôpitaux de Paris; Paris France

Funder

Rockefeller University Center for Clinical and Translational Science

Rockefeller University

March of Dimes

Dana Foundation

ANR, INSERM, and PHRC

University San Raffaele

Legs Poix

Deutsche Forschungsgemeinschaft

Bundesministerium für Bildung und Forschung

Sonnenfeldstiftung

Medical Faculty

Publisher

Wiley

Subject

Immunology,Immunology and Allergy

Reference133 articles.

1. Genetic structure and chromosomal mapping of MyD88;Hardiman;Genomics,1997

2. Molecular characterization and modular analysis of human MyD88;Hardiman;Oncogene,1996

3. Drosophila Toll and IL-1 receptor;Gay;Nature,1991

4. The product of the tobacco mosaic virus resistance gene N: similarity to toll and the interleukin-1 receptor;Whitham;Cell,1994

5. MyD88, an adapter protein involved in interleukin-1 signaling;Burns;J. Biol. Chem.,1998

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