CEACAM1 on activated NK cells inhibits NKG2D-mediated cytolytic function and signaling

Author:

Hosomi Shuhei1,Chen Zhangguo12,Baker Kristi1,Chen Lanfen1,Huang Yu-Hwa1,Olszak Torsten1,Zeissig Sebastian1,Wang Jing H.2,Mandelboim Ofer3,Beauchemin Nicole4,Lanier Lewis L.5,Blumberg Richard S.1

Affiliation:

1. Division of Gastroenterology; Department of Medicine; Brigham and Women's Hospital; Harvard Medical School; Boston MA USA

2. Department of Immunology; National Jewish Health; University of Colorado Denver; Denver CO USA

3. Lautenberg Center for General and Tumor Immunology; Hebrew University Hadassah Medical School; Jerusalem Israel

4. Goodman Cancer Research Centre and Departments of Biochemistry; Medicine and Oncology; McGill University; Montreal Canada

5. Department of Microbiology and Immunology and the Cancer Research Institute; University of California San Francisco; San Francisco CA USA

Funder

NIH

Harvard Digestive Diseases Center

Deutsche Forschungsgemeinschaft

Publisher

Wiley

Subject

Immunology,Immunology and Allergy

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