Partial MHC class II constructs inhibit MIF/CD74 binding and downstream effects
Author:
Affiliation:
1. Department of Internal Medicine; Section of Rheumatology; Yale University School of Medicine; New Haven; CT; USA
2. Department of Neurology; Oregon Health & Science University; Portland; OR; USA
Publisher
Wiley
Subject
Immunology,Immunology and Allergy
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1002/eji.201243162/fullpdf
Reference42 articles.
1. Macrophage migration inhibitory factor: a regulator of innate immunity;Calandra;Nat. Rev. Immunol.,2003
2. MIF signal transduction initiated by binding to CD74;Leng;J. Exp. Med.,2003
3. MIF is a noncognate ligand of CXC chemokine receptors in inflammatory and atherogenic cell recruitment;Bernhagen;Nat Med.,2007
4. A functional heteromeric MIF receptor formed by CD74 and CXCR4;Schwartz;FEBS lett.,2009
5. CD44 is the signaling component of the macrophage migration inhibitory factor-CD74 receptor complex;Shi;Immunity,2006
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