CD73 expression on extracellular vesicles derived from CD4+CD25+Foxp3+T cells contributes to their regulatory function-Reference-Cited by-同舟云学术

CD73 expression on extracellular vesicles derived from CD4+CD25+Foxp3+T cells contributes to their regulatory function

Published:2013-07-15 Issue:9 Volume:43 Page:2430-2440
ISSN:0014-2980
Container-title:European Journal of Immunology
language:en
Short-container-title:Eur. J. Immunol.

Author:

Smyth Lesley Ann¹,Ratnasothy Kulachelvy¹,Tsang Julia Y. S.²,Boardman Dominic¹,Warley Alice³,Lechler Robert¹,Lombardi Giovanna¹

Affiliation:

1. MRC Centre for Transplantation; King's College London, Guy's Hospital; London UK

2. Department of Anatomical and Cellular Pathology; University of Hong Kong; Hong Kong SAR China

3. Centre for Ultrastructural Imaging, King's College London; Guy's Campus; London UK

Funder

British Heart Foundation. Medical Research Council (MRC)

Centre for Transplantation, King's College London, UK

National Institute for Health Research (NIHR)

Biomedical Research Centre based at Guy's

St Thomas’ NHS Foundation Trust

King's College London

Publisher

Wiley

Subject

Immunology,Immunology and Allergy

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/eji.201242909/fullpdf

Reference37 articles.

1. Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases;Sakaguchi;J. Immunol.,1995

2. How regulatory T cells work;Vignali;Nat. Rev. Immunol.,2009

3. Phenotypical and functional specialization of FOXP3+ regulatory T cells;Campbell;Nat. Rev. Immunol.,2011

4. Adenosine generation catalyzed by CD39 and CD73 expressed on regulatory T cells mediates immune suppression;Deaglio;J. Exp. Med.,2007

5. T regulatory and primed uncommitted CD4 T cells express CD73, which suppresses effector CD4 T cells by converting 5’-adenosine monophosphate to adenosine;Kobie;J. Immunol.,2006

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