Effects of Renal Impairment and Hepatic Impairment on the Pharmacokinetics of Hydrocodone After Administration of a Hydrocodone Extended-Release Tablet Formulated With Abuse-Deterrence Technology

Author:

Darwish Mona1,Yang Ronghua2,Tracewell William3,Robertson Philmore3,Bond Mary2

Affiliation:

1. Sci-Med Bridge; LLC; Malvern PA USA

2. Teva Pharmaceuticals; Frazer PA USA

3. Teva Pharmaceuticals; West Chester PA USA

Funder

Cephalon

Teva Branded Pharmaceutical Products R & D, Inc.

Publisher

Wiley

Subject

Pharmacology (medical),Pharmaceutical Science

Reference30 articles.

1. Pain in hemodialysis patients: prevalence, cause, severity, and management;Davison;Am J Kidney Dis,2003

2. Opioids in renal failure and dialysis patients;Dean;J Pain Symptom Manage,2004

3. Pharmacokinetics and dosage adjustment in patients with hepatic dysfunction;Verbeeck;Eur J Clin Pharmacol,2008

4. IMS Institute for Healthcare Informatics The use of medicines in the United States: review of 2011 http://www.environmentalhealthnews.org/ehs/news/2013/pdf-links/IHII_Medicines_in_U.S_Report_2011-1.pdf 2012

5. CIMA LABS Inc. OraGuard™: tamper-deterrent, alcohol-resistant extended release technology 2012 http://www.cimalabs.com/technology/oraguard

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