Targeting phosphatidylinositol 3‐kinase gamma (PI3Kγ): Discovery and development of its selective inhibitors-Reference-Cited by-同舟云学术

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Targeting phosphatidylinositol 3‐kinase gamma (PI3Kγ): Discovery and development of its selective inhibitors

Published:2020-12-10 Issue:3 Volume:41 Page:1599-1621
ISSN:0198-6325
Container-title:Medicinal Research Reviews
language:en
Short-container-title:Med Res Rev

Author:

Zhu Jingyu¹,Li Kan¹,Yu Li²,Chen Yun¹,Cai Yanfei¹,Jin Jian¹,Hou Tingjun³^ORCID

Affiliation:

1. School of Pharmaceutical Sciences Jiangnan University Wuxi Jiangsu China

2. School of Inspection and Testing Certification Changzhou Vocational Institute of Engineering Changzhou Jiangsu China

3. Hangzhou Institute of Innovative Medicine College of Pharmaceutical Sciences, Zhejiang University Hangzhou Zhejiang China

Funder

Fundamental Research Funds for the Central Universities

National Natural Science Foundation of China

Publisher

Wiley

Subject

Drug Discovery,Pharmacology,Molecular Medicine

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/med.21770

Reference100 articles.

1. Discovery of selective phosphatidylinositol 3-kinase inhibitors to treat hematological malignancies

2. Structure and function of phosphoinositide 3-kinases

3. Targeting PI3Kδ: Emerging Therapy for Chronic Lymphocytic Leukemia and Beyond

4. PI3K inhibitors in inflammation, autoimmunity and cancer

5. Class 1 PI3K Clinical Candidates and Recent Inhibitor Design Strategies: A Medicinal Chemistry Perspective

Cited by 28 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. PI3Kgamma promotes neutrophil extracellular trap formation by noncanonical pyroptosis in abdominal aortic aneurysm;JCI Insight;2024-07-18

2. Identification of novel covalent JAK3 inhibitors through consensus scoring virtual screening: integration of common feature pharmacophore and covalent docking;Molecular Diversity;2024-07-15

3. Designing Small Molecule PI3Kγ Inhibitors: A Review of Structure-Based Methods and Computational Approaches;Journal of Medicinal Chemistry;2024-06-19

4. Integration of Multicomplex‐Based Pharmacophore Modeling and Molecular Docking in Machine Learning‐Based Virtual Screening: Toward the Discovery of Novel PI3K Inhibitors;Advanced Theory and Simulations;2024-05-21

5. Optimization of virtual screening against phosphoinositide 3-kinase delta: Integration of common feature pharmacophore and multicomplex-based molecular docking;Computational Biology and Chemistry;2024-04

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