Resveratrol regulates inflammation and improves oxidative stress via Nrf2 signaling pathway: Therapeutic and biotechnological prospects

Author:

Shahcheraghi Seyed Hossein12ORCID,Salemi Fateme3,Small Shlomo4,Syed Suliman4,Salari Farzam5,Alam Waqas6ORCID,Cheang Wai San7,Saso Luciano8,Khan Haroon6ORCID

Affiliation:

1. Infectious Diseases Research Center, Shahid Sadoughi Hospital Shahid Sadoughi University of Medical Sciences Yazd Iran

2. Department of Medical Genetics, School of Medicine Shahid Sadoughi University of Medical Sciences Yazd Iran

3. School of Medicine Islamic Azad University of Medical Sciences Yazd Iran

4. New York Institute of Technology College of Osteopathic Medicine New York New York USA

5. Shahid Sadoughi University of Medical Sciences and Health Services Yazd Iran

6. Department of Pharmacy Abdul Wali Khan University Mardan Mardan Pakistan

7. State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences University of Macau, Avenida da Universidade Taipa China

8. Department of Physiology and Pharmacology “Vittorio Erspamer”Sapienza University Rome Italy

Abstract

AbstractUsually, in aerobic metabolism, natural materials including nucleic acids, proteins, and lipids can experience auxiliary injury by oxidative responses. This damage produced by reactive oxygen/nitrogen species has been identified as “oxidative stress.” As a natural polyphenol got from red wine and peanuts, resveratrol is one of the most eminent anti‐aging mixtures. Based on many studies', resveratrol hinders destructive effects of inflammatory causes and reactive oxygen radicals in several tissues. The nuclear erythroid 2‐related factor 2 is a factor related to transcription with anti‐inflammatory, antioxidant possessions which is complicated by enzyme biotransformation and biosynthesis of lipids and carbohydrates. This review provides current understanding and information about the character of resveratrol against oxidative stress and regulation of inflammation via Nrf2 signaling pathway.

Publisher

Wiley

Subject

Pharmacology

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3