The importance of improving cognitive flexibility in adolescents with anorexia nervosa: The case for cognitive remediation therapy

Author:

Timko C. Alix12ORCID,Schnabel Jiana23ORCID,Orloff Natalia C.24ORCID

Affiliation:

1. Department of Psychiatry, Perelman School of Medicine University of Pennsylvania Philadelphia Pennsylvania USA

2. Department of Child and Adolescent Psychiatry and Behavioral Sciences Children's Hospital of Philadelphia Philadelphia Pennsylvania USA

3. Department of Psychology and Neuroscience Temple University Philadelphia Pennsylvania USA

4. Equip Health Carlsbad California USA

Abstract

AbstractObjectiveInefficiencies in executive functioning (EF), more specifically cognitive flexibility and an overly detailed processing style, are frequently observed in individuals with Anorexia Nervosa (AN) and have been identified as potential targets in treatment. Cognitive Remediation Therapy (CRT) is an adjunctive treatment approach specifically designed to have a positive impact on EF. Mainly evaluated in adults, CRT has been criticized for its perceived ineffectiveness in promoting weight restoration or directly reducing eating disorder symptoms.MethodWe argue that we need to refocus our conceptual framework for using CRT as an adjunctive treatment and specifically explore its potential benefit in adolescents.ResultsAdolescence is a critical window for EF development during which CRT has the potential to have the most impact. While it may not specifically ameliorate eating disorder symptoms and directly improve weight gain, CRT may mitigate the impact of malnutrition on adolescent brain development, reduce attrition rates in treatment, and improve cognitive flexibility and (indirectly) other maintaining factors, thereby improving global functioning.DiscussionMore research needs to be done to understand the development of EF in adolescents with AN and how best to employ CRT as an adjunctive treatment to support development and target maintaining factors. The current article broadly reviews findings on executive functioning inefficiencies in adolescents with AN and discusses the purpose and role of CRT in treating AN. Finally, we highlight key critiques of using CRT and pose questions for future research.Public SignificanceTreatments targeting executive functioning in adolescents with AN are limited. We need to better understand how CRT can benefit adolescents in treatment. Increasing treatment options, including adjunctive treatments, is necessary to reduce the long‐term impact of AN.

Funder

National Institute of Mental Health

Publisher

Wiley

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