Testing the role of associative learning in evidence‐based treatments for anorexia nervosa

Author:

Reilly Erin E.1ORCID,Wierenga Christina E.2ORCID,Le Grange Daniel13ORCID

Affiliation:

1. Department of Psychiatry and Behavioral Sciences University of California San Francisco California USA

2. Department of Psychiatry University of California La Jolla California USA

3. Department of Psychiatry & Behavioral Neuroscience (Emeritus) The University of Chicago Chicago Illinois USA

Abstract

AbstractTreatments for anorexia nervosa (AN) remain ineffective for many patients. Processes that can account for differential treatment outcomes remain mostly unknown. We propose that the field test the role of associative learning in current psychological treatments. We hold that this line of research could yield actionable information for understanding non‐response and improving long‐term outcomes. To make this argument, we define associative learning and outline its proposed role in understanding psychiatric disorders and their treatment. We then briefly review data exploring associative learning in AN. We argue that associative learning processes are implicitly implicated in existing treatments; by this rationale, baseline differences in learning may interfere with treatment response. Finally, we outline future research to test our hypotheses. Altogether, future research aimed at better understanding how associative learning may contribute to AN symptom persistence has the potential to inform novel directions in intervention research.Public SignificanceThere is a pressing need to improve outcomes in treatments for anorexia nervosa (AN). We propose that individual differences in associative learning—the ability to form and update associations between cues, contexts, behaviors, and outcomes—may account for differential response to existing treatments. Undertaking this research could provide an understanding of how current treatments work and inform new approaches for those who may be at risk of poor outcomes.

Funder

National Institute of Mental Health

Publisher

Wiley

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